Cas4–Cas1 fusions drive efficient PAM selection and control CRISPR adaptation

Microbes have the unique ability to acquire immunological memories from mobile genetic invaders to protect themselves from predation. To confer CRISPR resistance, new spacers need to be compatible with a targeting requirement in the invader's DNA called the protospacer adjacent motif (PAM). Man...

Descripción completa

Detalles Bibliográficos
Autores principales: Almendros, Cristóbal, Nobrega, Franklin L, McKenzie, Rebecca E, Brouns, Stan J J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547450/
https://www.ncbi.nlm.nih.gov/pubmed/30937444
http://dx.doi.org/10.1093/nar/gkz217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547450/
https://www.ncbi.nlm.nih.gov/pubmed/30937444
http://dx.doi.org/10.1093/nar/gkz217

Ejemplares similares