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DeepTACT: predicting 3D chromatin contacts via bootstrapping deep learning

Interactions between regulatory elements are of crucial importance for the understanding of transcriptional regulation and the interpretation of disease mechanisms. Hi-C technique has been developed for genome-wide detection of chromatin contacts. However, unless extremely deep sequencing is perform...

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Detalles Bibliográficos
Autores principales: Li, Wenran, Wong, Wing Hung, Jiang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547469/
https://www.ncbi.nlm.nih.gov/pubmed/30869141
http://dx.doi.org/10.1093/nar/gkz167