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β-Asarone increases doxorubicin sensitivity by suppressing NF-κB signaling and abolishes doxorubicin-induced enrichment of stem-like population by destabilizing Bmi1

BACKGROUND: Lymphoma is one of the most common hematologic malignancy. Drug resistance is the main obstacle faced in lymphoma treatment. Cancer stem cells are considered as the source of tumor recurrence, metastasis and drug resistance. The β-Asarone, a low-toxicity compound from the traditional med...

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Detalles Bibliográficos
Autores principales: Lv, Li-Na, Wang, Xiao-Chao, Tao, Li-Ju, Li, Hong-Wen, Li, Shu-You, Zheng, Fei-Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547485/
https://www.ncbi.nlm.nih.gov/pubmed/31171917
http://dx.doi.org/10.1186/s12935-019-0873-3