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miR-449a inhibits cell proliferation, migration, and inflammation by regulating high-mobility group box protein 1 and forms a mutual inhibition loop with Yin Yang 1 in rheumatoid arthritis fibroblast-like synoviocytes

BACKGROUND: We previously found that high-mobility group box protein 1 (HMGB1) promoted cell proliferation, migration, invasion, and autophagy in rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS), but little is known about its regulatory mechanism. The aim of this study was to investigate t...

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Detalles Bibliográficos
Autores principales: Cai, Yongsong, Jiang, Congshan, Zhu, Jialin, Xu, Ke, Ren, Xiaoyu, Xu, Lin, Hu, Peijing, Wang, Bo, Yuan, Qiling, Guo, Yuanxu, Sun, Jian, Xu, Peng, Qiu, Yusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547523/
https://www.ncbi.nlm.nih.gov/pubmed/31159863
http://dx.doi.org/10.1186/s13075-019-1920-0