Arginase impairs hypoxic pulmonary vasoconstriction in murine endotoxemia

BACKGROUND: Hypoxic pulmonary vasoconstriction (HPV) optimizes the match between ventilation and perfusion in the lung by reducing blood flow to poorly ventilated regions. Sepsis and endotoxemia impair HPV. We previously showed that nitric oxide synthase 2 (NOS2) is required, but not sufficient, for...

Descripción completa

Detalles Bibliográficos
Autores principales: Petersen, Bodil, Busch, Cornelius J., Schleifer, Grigorij, Schaack, Dominik, Lasitschka, Felix, Bloch, Kenneth D., Bloch, Donald B., Ichinose, Fumito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547543/
https://www.ncbi.nlm.nih.gov/pubmed/31159807
http://dx.doi.org/10.1186/s12931-019-1062-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547543/
https://www.ncbi.nlm.nih.gov/pubmed/31159807
http://dx.doi.org/10.1186/s12931-019-1062-6

Ejemplares similares