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A comparison of RNA extraction and sequencing protocols for detection of small RNAs in plasma

BACKGROUND: Circulating microRNAs (miRNAs) are attractive non-invasive biomarkers for a variety of conditions due to their stability and altered pathophysiological expression levels. Reliable detection of global expression profiles is required to maximise miRNA biomarker discovery. Although developm...

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Detalles Bibliográficos
Autores principales: Wong, Ryan K.Y., MacMahon, Meabh, Woodside, Jayne V., Simpson, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547578/
https://www.ncbi.nlm.nih.gov/pubmed/31159762
http://dx.doi.org/10.1186/s12864-019-5826-7