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Endo-lysosomal dysregulations and late-onset Alzheimer’s disease: impact of genetic risk factors
Increasing evidence supports that cellular dysregulations in the degradative routes contribute to the initiation and progression of neurodegenerative diseases, including Alzheimer’s disease. Autophagy and endolysosomal homeostasis need to be maintained throughout life as they are major cellular mech...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547588/ https://www.ncbi.nlm.nih.gov/pubmed/31159836 http://dx.doi.org/10.1186/s13024-019-0323-7 |