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Endo-lysosomal dysregulations and late-onset Alzheimer’s disease: impact of genetic risk factors

Increasing evidence supports that cellular dysregulations in the degradative routes contribute to the initiation and progression of neurodegenerative diseases, including Alzheimer’s disease. Autophagy and endolysosomal homeostasis need to be maintained throughout life as they are major cellular mech...

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Detalles Bibliográficos
Autores principales: Van Acker, Zoë P., Bretou, Marine, Annaert, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547588/
https://www.ncbi.nlm.nih.gov/pubmed/31159836
http://dx.doi.org/10.1186/s13024-019-0323-7