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New insights into YAP/TAZ nucleo‐cytoplasmic shuttling: new cancer therapeutic opportunities?
Yes‐associated protein (YAP) and transcriptional co‐activator with PDZ‐binding motif (TAZ), the main effectors of the Hippo pathway, are emerging as important players in cancer biology and therapy response. The intracellular localization of YAP/TAZ is a key determinant in the regulation of their act...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547617/ https://www.ncbi.nlm.nih.gov/pubmed/31050214 http://dx.doi.org/10.1002/1878-0261.12498 |