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Development of an anti‐BAG3 humanized antibody for treatment of pancreatic cancer

We have previously shown that secreted BAG3 is a potential target for the treatment of pancreatic ductal adenocarcinoma and that pancreatic tumor growth and metastatic dissemination can be reduced by treatment with an anti‐BAG3 murine antibody. Here, we used complementarity‐determining region (CDR)...

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Detalles Bibliográficos
Autores principales: Basile, Anna, De Marco, Margot, Festa, Michelina, Falco, Antonia, Iorio, Vittoria, Guerriero, Luana, Eletto, Daniela, Rea, Domenica, Arra, Claudio, Lamolinara, Alessia, Ballerini, Patrizia, Damiani, Verena, Rosati, Alessandra, Sala, Gianluca, Turco, Maria Caterina, Marzullo, Liberato, De Laurenzi, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547619/
https://www.ncbi.nlm.nih.gov/pubmed/30973679
http://dx.doi.org/10.1002/1878-0261.12492