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Qß Virus-like particle-based vaccine induces robust immunity and protects against tauopathy

Tauopathies, including frontotemporal dementia (FTD) and Alzheimer’s disease (AD) are progressive neurodegenerative diseases clinically characterized by cognitive decline and could be caused by the aggregation of hyperphosphorylated pathological tau (pTau) as neurofibrillary tangles (NFTs) inside ne...

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Detalles Bibliográficos
Autores principales: Maphis, Nicole M., Peabody, Julianne, Crossey, Erin, Jiang, Shanya, Jamaleddin Ahmad, Fadi A., Alvarez, Maria, Mansoor, Soiba Khalid, Yaney, Amanda, Yang, Yirong, Sillerud, Laurel O., Wilson, Colin M., Selwyn, Reed, Brigman, Jonathan L., Cannon, Judy L., Peabody, David S., Chackerian, Bryce, Bhaskar, Kiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547647/
https://www.ncbi.nlm.nih.gov/pubmed/31231552
http://dx.doi.org/10.1038/s41541-019-0118-4