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Hematopoietic stem and progenitor cell proliferation and differentiation requires the trithorax protein Ash2l
Post-translational modifications of core histones participate in controlling the expression of genes. Methylation of lysine 4 of histone H3 (H3K4), together with acetylation of H3K27, is closely associated with open chromatin and gene transcription. H3K4 methylation is catalyzed by KMT2 lysine methy...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547667/ https://www.ncbi.nlm.nih.gov/pubmed/31164666 http://dx.doi.org/10.1038/s41598-019-44720-3 |