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Alternative splicing-derived intersectin1-L and intersectin1-S exert opposite function in glioma progression

Intersectin1 (ITSN1) contains two isoforms: ITSN1-S and ITSN1-L, which is highly regulated by alternative splicing. However, the alteration of alternative splicing and its importance in cancer is still unknown. In this study, our transcriptome analysis by using a large glioma cohort indicated the tw...

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Detalles Bibliográficos
Autores principales: Shao, Ying, Chong, Wei, Liu, Xiaoli, Xu, Yun, Zhang, Huikun, Xu, Qiao, Guo, Zhifang, Zhao, Yawen, Zhang, Ming, Ma, Yongjie, Gu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547669/
https://www.ncbi.nlm.nih.gov/pubmed/31160551
http://dx.doi.org/10.1038/s41419-019-1668-0