A synthesis strategy for tetracyclic terpenoids leads to agonists of ERβ

Natural product and natural product-like molecules continue to be important for the development of pharmaceutical agents, as molecules in this class play a vital role in the pipeline for new therapeutics. Among these, tetracyclic terpenoids are privileged, with >100 being FDA-approved drugs. Desp...

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Detalles Bibliográficos
Autores principales: Kim, Wan Shin, Shalit, Zachary A., Nguyen, Sidney M., Schoepke, Emmalie, Eastman, Alan, Burris, Thomas P., Gaur, Arti B., Micalizio, Glenn C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547701/
https://www.ncbi.nlm.nih.gov/pubmed/31164645
http://dx.doi.org/10.1038/s41467-019-10415-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547701/
https://www.ncbi.nlm.nih.gov/pubmed/31164645
http://dx.doi.org/10.1038/s41467-019-10415-6

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