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A synthesis strategy for tetracyclic terpenoids leads to agonists of ERβ
Natural product and natural product-like molecules continue to be important for the development of pharmaceutical agents, as molecules in this class play a vital role in the pipeline for new therapeutics. Among these, tetracyclic terpenoids are privileged, with >100 being FDA-approved drugs. Desp...
Autores principales: | Kim, Wan Shin, Shalit, Zachary A., Nguyen, Sidney M., Schoepke, Emmalie, Eastman, Alan, Burris, Thomas P., Gaur, Arti B., Micalizio, Glenn C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547701/ https://www.ncbi.nlm.nih.gov/pubmed/31164645 http://dx.doi.org/10.1038/s41467-019-10415-6 |
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