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Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B

Muscle loss due to fibrotic or adipogenic replacement of myofibers is common in muscle diseases and muscle-resident fibro/adipogenic precursors (FAPs) are implicated in this process. While FAP-mediated muscle fibrosis is widely studied in muscle diseases, the role of FAPs in adipogenic muscle loss i...

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Detalles Bibliográficos
Autores principales: Hogarth, Marshall W., Defour, Aurelia, Lazarski, Christopher, Gallardo, Eduard, Diaz Manera, Jordi, Partridge, Terence A., Nagaraju, Kanneboyina, Jaiswal, Jyoti K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547715/
https://www.ncbi.nlm.nih.gov/pubmed/31160583
http://dx.doi.org/10.1038/s41467-019-10438-z