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p38α MAPK inhibition translates to cell cycle re-entry of neonatal rat ventricular cardiomyocytes and de novo nestin expression in response to thrombin and after apex resection

The present study tested the hypothesis that p38α MAPK inhibition leads to cell cycle re-entry of neonatal ventricular cardiomyocytes (NNVMs) and de novo nestin expression in response to thrombin and after apex resection of the neonatal rat heart. Thrombin (1 U/ml) treatment of 1-day old NNVMs did n...

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Detalles Bibliográficos
Autores principales: Hertig, Vanessa, Brezai, Andra, Bergeron, Alexandre, Villeneuve, Louis, Gillis, Marc-Antoine, Calderone, Angelino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547723/
https://www.ncbi.nlm.nih.gov/pubmed/31160695
http://dx.doi.org/10.1038/s41598-019-44712-3