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Loss of PICH promotes chromosome instability and cell death in triple-negative breast cancer

Triple-negative breast cancer (TNBC), defined by the lack of expression of estrogen, progesterone, and ERBB2 receptors, has the worst prognosis of all breast cancers. It is difficult to treat owing to a lack of effective molecular targets. Here, we report that the growth of TNBC cells is exceptional...

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Detalles Bibliográficos
Autores principales: Huang, Yan, Li, Wanjin, Yan, Weiwei, Wu, Jiaqi, Chen, Liang, Yao, Xiaohong, Gu, Feng, Lv, Luye, Zhao, Jiangman, Zhao, Ming, Xia, Tian, Han, Qiuying, Li, Teng, Ying, Xiaomin, Li, Tao, Xia, Qing, Li, Ailing, Zhang, Xuemin, Chen, Yuan, Zhou, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547724/
https://www.ncbi.nlm.nih.gov/pubmed/31160555
http://dx.doi.org/10.1038/s41419-019-1662-6