Potent and specific MTH1 inhibitors targeting gastric cancer

Human mutT homolog 1(MTH1), the oxidized dNTP pool sanitizer enzyme, has been reported to be highly expressed in various malignant tumors. However, the oncogenic role of MTH1 in gastric cancer remains to be determined. In the current study, we found that MTH1 was overexpressed in human gastric cance...

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Detalles Bibliográficos
Autores principales: Zhou, Wenjuan, Ma, Liying, Yang, Jing, Qiao, Hui, Li, Lingyu, Guo, Qian, Ma, Jinlian, Zhao, Lijuan, Wang, Junwei, Jiang, Guozhong, Wan, Xiangbin, Adam Goscinski, Mariusz, Ding, Lina, Zheng, Yichao, Li, Wencai, Liu, Hongmin, Suo, Zhenhe, Zhao, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547740/
https://www.ncbi.nlm.nih.gov/pubmed/31164636
http://dx.doi.org/10.1038/s41419-019-1665-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547740/
https://www.ncbi.nlm.nih.gov/pubmed/31164636
http://dx.doi.org/10.1038/s41419-019-1665-3

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