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The crystal structure of an antiparallel chair-type G-quadruplex formed by Bromo-substituted human telomeric DNA
Human telomeric guanine-rich DNA, which could adopt different G-quadruplex structures, plays important roles in protecting the cell from recombination and degradation. Although many of these structures were determined, the chair-type G-quadruplex structure remains elusive. Here, we present a crystal...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547763/ https://www.ncbi.nlm.nih.gov/pubmed/30957851 http://dx.doi.org/10.1093/nar/gkz221 |