The crystal structure of an antiparallel chair-type G-quadruplex formed by Bromo-substituted human telomeric DNA

Human telomeric guanine-rich DNA, which could adopt different G-quadruplex structures, plays important roles in protecting the cell from recombination and degradation. Although many of these structures were determined, the chair-type G-quadruplex structure remains elusive. Here, we present a crystal...

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Detalles Bibliográficos
Autores principales: Geng, Yanyan, Liu, Changdong, Zhou, Bo, Cai, Qixu, Miao, Haitao, Shi, Xiao, Xu, Naining, You, Yingying, Fung, Chun Po, Din, Rahman Ud, Zhu, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547763/
https://www.ncbi.nlm.nih.gov/pubmed/30957851
http://dx.doi.org/10.1093/nar/gkz221

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