Cargando…

An analysis of large structural variation in global Plasmodium falciparum isolates identifies a novel duplication of the chloroquine resistance associated gene

The evolution of genetic mechanisms for host immune evasion and anti-malarial resistance has enabled the Plasmodium falciparum malaria parasite to inflict high morbidity and mortality on human populations. Most studies of P. falciparum genetic diversity have focused on single-nucleotide polymorphism...

Descripción completa

Detalles Bibliográficos
Autores principales: Ravenhall, Matt, Benavente, Ernest Diez, Sutherland, Colin J., Baker, David A., Campino, Susana, Clark, Taane G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547842/
https://www.ncbi.nlm.nih.gov/pubmed/31164664
http://dx.doi.org/10.1038/s41598-019-44599-0