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An analysis of large structural variation in global Plasmodium falciparum isolates identifies a novel duplication of the chloroquine resistance associated gene
The evolution of genetic mechanisms for host immune evasion and anti-malarial resistance has enabled the Plasmodium falciparum malaria parasite to inflict high morbidity and mortality on human populations. Most studies of P. falciparum genetic diversity have focused on single-nucleotide polymorphism...
Autores principales: | Ravenhall, Matt, Benavente, Ernest Diez, Sutherland, Colin J., Baker, David A., Campino, Susana, Clark, Taane G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547842/ https://www.ncbi.nlm.nih.gov/pubmed/31164664 http://dx.doi.org/10.1038/s41598-019-44599-0 |
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