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T cell anergy in perinatal mice is promoted by T reg cells and prevented by IL-33

Perinatal T cells broadly access nonlymphoid tissues, where they are exposed to sessile tissue antigens. To probe the outcome of such encounters, we examined the defective elimination of self-reactive clones in Aire-deficient mice. Nonlymphoid tissues were sequentially seeded by distinct waves of CD...

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Detalles Bibliográficos
Autores principales: Tuncel, Jonatan, Benoist, Christophe, Mathis, Diane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547863/
https://www.ncbi.nlm.nih.gov/pubmed/30988052
http://dx.doi.org/10.1084/jem.20182002