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Metabolically activated adipose tissue macrophages link obesity to triple-negative breast cancer

Obesity is associated with increased incidence and severity of triple-negative breast cancer (TNBC); however, mechanisms underlying this relationship are incompletely understood. Here, we show that obesity reprograms mammary adipose tissue macrophages to a pro-inflammatory metabolically activated ph...

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Detalles Bibliográficos
Autores principales: Tiwari, Payal, Blank, Ariane, Cui, Chang, Schoenfelt, Kelly Q., Zhou, Guolin, Xu, Yanfei, Khramtsova, Galina, Olopade, Funmi, Shah, Ajay M., Khan, Seema A., Rosner, Marsha Rich, Becker, Lev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547867/
https://www.ncbi.nlm.nih.gov/pubmed/31053611
http://dx.doi.org/10.1084/jem.20181616