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Predictive Approach Identifies Molecular Targets and Interventions to Restore Angiogenesis in Wounds With Delayed Healing

Impaired angiogenesis is a hallmark of wounds with delayed healing, and currently used therapies to restore angiogenesis have limited efficacy. Here, we employ a computational simulation-based approach to identify influential molecular and cellular processes, as well as protein targets, whose modula...

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Detalles Bibliográficos
Autores principales: Nagaraja, Sridevi, Chen, Lin, DiPietro, Luisa A., Reifman, Jaques, Mitrophanov, Alexander Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547939/
https://www.ncbi.nlm.nih.gov/pubmed/31191342
http://dx.doi.org/10.3389/fphys.2019.00636