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Predictive Approach Identifies Molecular Targets and Interventions to Restore Angiogenesis in Wounds With Delayed Healing
Impaired angiogenesis is a hallmark of wounds with delayed healing, and currently used therapies to restore angiogenesis have limited efficacy. Here, we employ a computational simulation-based approach to identify influential molecular and cellular processes, as well as protein targets, whose modula...
Autores principales: | Nagaraja, Sridevi, Chen, Lin, DiPietro, Luisa A., Reifman, Jaques, Mitrophanov, Alexander Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547939/ https://www.ncbi.nlm.nih.gov/pubmed/31191342 http://dx.doi.org/10.3389/fphys.2019.00636 |
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