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Junctional tumor suppressors interact with 14-3-3 proteins to control planar spindle alignment
Proper orientation of the mitotic spindle is essential for cell fate determination, tissue morphogenesis, and homeostasis. During epithelial proliferation, planar spindle alignment ensures the maintenance of polarized tissue architecture, and aberrant spindle orientation can disrupt epithelial integ...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548121/ https://www.ncbi.nlm.nih.gov/pubmed/31088859 http://dx.doi.org/10.1083/jcb.201803116 |