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Junctional tumor suppressors interact with 14-3-3 proteins to control planar spindle alignment

Proper orientation of the mitotic spindle is essential for cell fate determination, tissue morphogenesis, and homeostasis. During epithelial proliferation, planar spindle alignment ensures the maintenance of polarized tissue architecture, and aberrant spindle orientation can disrupt epithelial integ...

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Detalles Bibliográficos
Autores principales: Nakajima, Yu-ichiro, Lee, Zachary T., McKinney, Sean A., Swanson, Selene K., Florens, Laurence, Gibson, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548121/
https://www.ncbi.nlm.nih.gov/pubmed/31088859
http://dx.doi.org/10.1083/jcb.201803116