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Necroptosis mediators RIPK3 and MLKL suppress intracellular Listeria replication independently of host cell killing

RIPK3, a key mediator of necroptosis, has been implicated in the host defense against viral infection primary in immune cells. However, gene expression analysis revealed that RIPK3 is abundantly expressed not only in immune organs but also in the gastrointestinal tract, particularly in the small int...

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Detalles Bibliográficos
Autores principales: Sai, Kazuhito, Parsons, Cameron, House, John S., Kathariou, Sophia, Ninomiya-Tsuji, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548127/
https://www.ncbi.nlm.nih.gov/pubmed/30975711
http://dx.doi.org/10.1083/jcb.201810014