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Peroxisome protein import recapitulated in Xenopus egg extracts

Peroxisomes import their luminal proteins from the cytosol. Most substrates contain a C-terminal Ser-Lys-Leu (SKL) sequence that is recognized by the receptor Pex5. Pex5 binds to peroxisomes via a docking complex containing Pex14, and recycles back into the cytosol following its mono-ubiquitination...

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Detalles Bibliográficos
Autores principales: Romano, Fabian B., Blok, Neil B., Rapoport, Tom A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548129/
https://www.ncbi.nlm.nih.gov/pubmed/30971414
http://dx.doi.org/10.1083/jcb.201901152