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Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122

Importins ferry proteins into nuclei while exportins carry cargoes to the cytoplasm. In the accompanying paper in this issue (Vera Rodriguez et al. 2019. J. Cell Biol. https://doi.org/10.1083/jcb.201812091), we discovered that Pdr6 is a biportin that imports, e.g., the SUMO E2 ligase Ubc9 while depl...

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Detalles Bibliográficos
Autores principales: Aksu, Metin, Trakhanov, Sergei, Vera Rodriguez, Arturo, Görlich, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548137/
https://www.ncbi.nlm.nih.gov/pubmed/31023722
http://dx.doi.org/10.1083/jcb.201812093