Respiratory chain inactivation links cartilage-mediated growth retardation to mitochondrial diseases

In childhood, skeletal growth is driven by transient expansion of cartilage in the growth plate. The common belief is that energy production in this hypoxic tissue mainly relies on anaerobic glycolysis and not on mitochondrial respiratory chain (RC) activity. However, children with mitochondrial dis...

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Detalles Bibliográficos
Autores principales: Holzer, Tatjana, Probst, Kristina, Etich, Julia, Auler, Markus, Georgieva, Veronika S., Bluhm, Björn, Frie, Christian, Heilig, Juliane, Niehoff, Anja, Nüchel, Julian, Plomann, Markus, Seeger, Jens M., Kashkar, Hamid, Baris, Olivier R., Wiesner, Rudolf J., Brachvogel, Bent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548139/
https://www.ncbi.nlm.nih.gov/pubmed/31085560
http://dx.doi.org/10.1083/jcb.201809056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548139/
https://www.ncbi.nlm.nih.gov/pubmed/31085560
http://dx.doi.org/10.1083/jcb.201809056

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