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BRCA Genes: The Role in Genome Stability, Cancer Stemness and Therapy Resistance
Carcinogenesis is a multistep process, and tumors frequently harbor multiple mutations regulating genome integrity, cell division and death. The integrity of cellular genome is closely controlled by the mechanisms of DNA damage signaling and DNA repair. The association of breast cancer susceptibilit...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548160/ https://www.ncbi.nlm.nih.gov/pubmed/31205572 http://dx.doi.org/10.7150/jca.30410 |