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Cytochalasin H Inhibits Angiogenesis via the Suppression of HIF-1α Protein Accumulation and VEGF Expression through PI3K/AKT/P70S6K and ERK1/2 Signaling Pathways in Non-Small Cell Lung Cancer Cells

Our previous study has demonstrated that cytochalasin H (CyH) isolated from mangrove-derived endophytic fungus induces apoptosis and inhibits migration in A549 non-small cell lung cancer (NSCLC) cells. In this study, we further explored the effect of CyH on angiogenesis in NSCLC cells and the underl...

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Detalles Bibliográficos
Autores principales: Ma, Yuefan, Xiu, Zihan, Zhou, Zhiyuan, Huang, Bingyu, Liu, Jiao, Wu, Xiaofeng, Li, Sanzhong, Tang, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548170/
https://www.ncbi.nlm.nih.gov/pubmed/31205560
http://dx.doi.org/10.7150/jca.29933