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Disease Progression and Pharmacological Intervention in a Nutrient-Deficient Rat Model of Nonalcoholic Steatohepatitis

BACKGROUND: There is a marked need for improved animal models of nonalcoholic steatohepatitis (NASH) to facilitate the development of more efficacious drug therapies for the disease. METHODS: Here, we investigated the development of fibrotic NASH in male Wistar rats fed a choline-deficient l-amino a...

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Detalles Bibliográficos
Autores principales: Tølbøl, Kirstine S., Stierstorfer, Birgit, Rippmann, Jörg F., Veidal, Sanne S., Rigbolt, Kristoffer T. G., Schönberger, Tanja, Gillum, Matthew P., Hansen, Henrik H., Vrang, Niels, Jelsing, Jacob, Feigh, Michael, Broermann, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548202/
https://www.ncbi.nlm.nih.gov/pubmed/30511198
http://dx.doi.org/10.1007/s10620-018-5395-7