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Recognition and stabilization of geranylgeranylated human Rab5 by the GDP Dissociation Inhibitor (GDI)
The small GTPase Rab5 is the key regulator of early endosomal fusion. It is post-translationally modified by covalent attachment of two geranylgeranyl (GG) chains to adjacent cysteine residues of the C-terminal hypervariable region (HVR). The GDP dissociation inhibitor (GDI) recognizes membrane-asso...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548291/ https://www.ncbi.nlm.nih.gov/pubmed/29065764 http://dx.doi.org/10.1080/21541248.2017.1371268 |