Normal epithelial cells trigger EphA2-dependent RasV12 cell repulsion at the single cell level

Epithelial cells expressing oncogenic Ras (RasV12) are detected by normal neighbors and are often extruded from tissues. We recently demonstrated that differential EphA2 signaling drives the segregation of mutant cells from normal monolayers via cell repulsion and increased RasV12 cell contractility...

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Detalles Bibliográficos
Autores principales: Hill, William, Hogan, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Brief Report - Commissioned
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548300/
https://www.ncbi.nlm.nih.gov/pubmed/28636467
http://dx.doi.org/10.1080/21541248.2017.1324940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548300/
https://www.ncbi.nlm.nih.gov/pubmed/28636467
http://dx.doi.org/10.1080/21541248.2017.1324940

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