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Normal epithelial cells trigger EphA2-dependent RasV12 cell repulsion at the single cell level
Epithelial cells expressing oncogenic Ras (RasV12) are detected by normal neighbors and are often extruded from tissues. We recently demonstrated that differential EphA2 signaling drives the segregation of mutant cells from normal monolayers via cell repulsion and increased RasV12 cell contractility...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548300/ https://www.ncbi.nlm.nih.gov/pubmed/28636467 http://dx.doi.org/10.1080/21541248.2017.1324940 |