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Inhibition by fluoxetine of LH-stimulated cyclic AMP synthesis in tumor Leydig cells partly involves AMPK activation

Fluoxetine (FLX), a widely used antidepressant primarily acting as a selective serotonin reuptake inhibitor (SSRI), has been shown to exhibit other mechanisms of action in various cell types. Consequently, it might have unexpected adverse effects not related to its intended use, possibly in the endo...

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Detalles Bibliográficos
Autores principales: Nguyen, Thi Mong Diep, Klett, Danièle, Filliatreau, Laura, Combarnous, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548379/
https://www.ncbi.nlm.nih.gov/pubmed/31163038
http://dx.doi.org/10.1371/journal.pone.0217519