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Noise-precision tradeoff in predicting combinations of mutations and drugs
Many biological problems involve the response to multiple perturbations. Examples include response to combinations of many drugs, and the effects of combinations of many mutations. Such problems have an exponentially large space of combinations, which makes it infeasible to cover the entire space ex...
Autores principales: | Tendler, Avichai, Zimmer, Anat, Mayo, Avi, Alon, Uri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548401/ https://www.ncbi.nlm.nih.gov/pubmed/31116755 http://dx.doi.org/10.1371/journal.pcbi.1006956 |
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