CBX2 is required to stabilize the testis pathway by repressing Wnt signaling

XX and XY fetal gonads are initially bipotential, poised between the ovary and testis fate. Multiple lines of evidence suggest that commitment to testis fate requires the repression of genes associated with ovary fate. It was previously shown that loss of CBX2, the subunit of the Polycomb Repressive...

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Detalles Bibliográficos
Autores principales: Garcia-Moreno, S. Alexandra, Lin, Yi-Tzu, Futtner, Christopher R., Salamone, Isabella M., Capel, Blanche, Maatouk, Danielle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548405/
https://www.ncbi.nlm.nih.gov/pubmed/31116734
http://dx.doi.org/10.1371/journal.pgen.1007895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548405/
https://www.ncbi.nlm.nih.gov/pubmed/31116734
http://dx.doi.org/10.1371/journal.pgen.1007895

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