Cargando…

Delivery of self-amplifying RNA vaccines in in vitro reconstituted virus-like particles

Many mRNA-based vaccines have been investigated for their specific potential to activate dendritic cells (DCs), the highly-specialized antigen-presenting cells of the immune system that play a key role in inducing effective CD4(+) and CD8(+) T-cell responses. In this paper we report a new vaccine/ge...

Descripción completa

Detalles Bibliográficos
Autores principales: Biddlecome, Adam, Habte, Habtom H., McGrath, Katherine M., Sambanthamoorthy, Sharmila, Wurm, Melanie, Sykora, Martina M., Knobler, Charles M., Lorenz, Ivo C., Lasaro, Marcio, Elbers, Knut, Gelbart, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548422/
https://www.ncbi.nlm.nih.gov/pubmed/31163034
http://dx.doi.org/10.1371/journal.pone.0215031