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Delivery of self-amplifying RNA vaccines in in vitro reconstituted virus-like particles
Many mRNA-based vaccines have been investigated for their specific potential to activate dendritic cells (DCs), the highly-specialized antigen-presenting cells of the immune system that play a key role in inducing effective CD4(+) and CD8(+) T-cell responses. In this paper we report a new vaccine/ge...
Autores principales: | Biddlecome, Adam, Habte, Habtom H., McGrath, Katherine M., Sambanthamoorthy, Sharmila, Wurm, Melanie, Sykora, Martina M., Knobler, Charles M., Lorenz, Ivo C., Lasaro, Marcio, Elbers, Knut, Gelbart, William M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548422/ https://www.ncbi.nlm.nih.gov/pubmed/31163034 http://dx.doi.org/10.1371/journal.pone.0215031 |
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