Cargando…
Overexpression of the Fork Protection Complex: a strategy to tolerate oncogene-induced replication stress in cancer cells
Oncogene-induced replication stress (RS) plays an active role in tumorigenesis by promoting genomic instability but is also a challenge for cell proliferation. Recent evidence indicates that different types of cancer cells adapt to RS by overexpressing components of the ATR-CHK1 pathway that promote...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548472/ https://www.ncbi.nlm.nih.gov/pubmed/31211234 http://dx.doi.org/10.1080/23723556.2019.1607455 |