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A chromatin-based signalling mechanism directs the switch from mutagenic to error-free repair of DNA double strand breaks
Mutations caused by DNA damage are a main driver of cancer. We discovered that recognition of newly synthesised histone H4 directs breast cancer type 1 susceptibility protein (BRCA1) to post-replicative chromatin. The switch from mutagenic to error-free DNA double strand break repair by homologous r...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548474/ https://www.ncbi.nlm.nih.gov/pubmed/31211233 http://dx.doi.org/10.1080/23723556.2019.1605820 |