Palmitate is not an effective fuel for pancreatic islets and amplifies insulin secretion independent of calcium release from endoplasmic reticulum

The aim of the study was to determine the acute contribution of fuel oxidation in mediating the increase in insulin secretion rate (ISR) in response to fatty acids. Measures of mitochondrial metabolism, as reflected by oxygen consumption rate (OCR) and cytochrome c reduction, calcium signaling, and...

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Detalles Bibliográficos
Autores principales: Kuok, Iok Teng, Rountree, Austin M., Jung, Seung-Ryoung, Sweet, Ian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548485/
https://www.ncbi.nlm.nih.gov/pubmed/31084524
http://dx.doi.org/10.1080/19382014.2019.1601490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548485/
https://www.ncbi.nlm.nih.gov/pubmed/31084524
http://dx.doi.org/10.1080/19382014.2019.1601490

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