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Autophagy represses hepatic carcinogenesis

Hepatocyte-specific knockout of the essential autophagy gene Autophagy-related 7 (Atg7) is sufficient to cause hepatic carcinogenesis. A recent paper by Lee et al. unveils the molecular pathway accounting for hepatic hypertrophy and hyperplasia followed by malignant transformation. This pathway invo...

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Detalles Bibliográficos
Autores principales: Paillet, Juliette, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548487/
https://www.ncbi.nlm.nih.gov/pubmed/31211229
http://dx.doi.org/10.1080/23723556.2019.1573080