Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism

CHC22 clathrin plays a key role in intracellular membrane traffic of the insulin-responsive glucose transporter GLUT4 in humans. We performed population genetic and phylogenetic analyses of the CHC22-encoding CLTCL1 gene, revealing independent gene loss in at least two vertebrate lineages, after ari...

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Detalles Bibliográficos
Autores principales: Fumagalli, Matteo, Camus, Stephane M, Diekmann, Yoan, Burke, Alice, Camus, Marine D, Norman, Paul J, Joseph, Agnel, Abi-Rached, Laurent, Benazzo, Andrea, Rasteiro, Rita, Mathieson, Iain, Topf, Maya, Parham, Peter, Thomas, Mark G, Brodsky, Frances M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548504/
https://www.ncbi.nlm.nih.gov/pubmed/31159924
http://dx.doi.org/10.7554/eLife.41517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548504/
https://www.ncbi.nlm.nih.gov/pubmed/31159924
http://dx.doi.org/10.7554/eLife.41517

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