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A combination of transcription factors mediates inducible interchromosomal contacts

The genome forms specific three-dimensional contacts in response to cellular or environmental conditions. However, it remains largely unknown which proteins specify and mediate such contacts. Here we describe an assay, MAP-C (Mutation Analysis in Pools by Chromosome conformation capture), that simul...

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Detalles Bibliográficos
Autores principales: Kim, Seungsoo, Dunham, Maitreya J, Shendure, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548505/
https://www.ncbi.nlm.nih.gov/pubmed/31081754
http://dx.doi.org/10.7554/eLife.42499