Cargando…

A combination of transcription factors mediates inducible interchromosomal contacts

The genome forms specific three-dimensional contacts in response to cellular or environmental conditions. However, it remains largely unknown which proteins specify and mediate such contacts. Here we describe an assay, MAP-C (Mutation Analysis in Pools by Chromosome conformation capture), that simul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Seungsoo, Dunham, Maitreya J, Shendure, Jay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Chromosomes and Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548505/ https://www.ncbi.nlm.nih.gov/pubmed/31081754 http://dx.doi.org/10.7554/eLife.42499

Ejemplares similares

The dynamic three-dimensional organization of the diploid yeast genome
por: Kim, Seungsoo, et al.
Publicado: (2017)

Systematic analysis of naturally occurring insertions and deletions that alter transcription factor spacing identifies tolerant and sensitive transcription factor pairs
por: Shen, Zeyang, et al.
Publicado: (2022)

Crl activates transcription by stabilizing active conformation of the master stress transcription initiation factor
por: Xu, Juncao, et al.
Publicado: (2019)

Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm
por: Yang, Xinan H, et al.
Publicado: (2017)

Vernalization-triggered expression of the antisense transcript COOLAIR is mediated by CBF genes
por: Jeon, Myeongjune, et al.
Publicado: (2023)

Transcription factor clusters regulate genes in eukaryotic cells
por: Wollman, Adam JM, et al.
Publicado: (2017)

Transcription elongation is finely tuned by dozens of regulatory factors
por: Couvillion, Mary, et al.
Publicado: (2022)

Correction: Transcription factor clusters regulate genes in eukaryotic cells
por: Wollman, Adam JM, et al.
Publicado: (2019)

piRNA-guided co-transcriptional silencing coopts nuclear export factors
por: Fabry, Martin H, et al.
Publicado: (2019)

ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription
por: Riou, Rozenn, et al.
Publicado: (2020)

Simple biochemical features underlie transcriptional activation domain diversity and dynamic, fuzzy binding to Mediator
por: Sanborn, Adrian L, et al.
Publicado: (2021)

Dissociation rate compensation mechanism for budding yeast pioneer transcription factors
por: Donovan, Benjamin T, et al.
Publicado: (2019)

Arabidopsis RNA processing factor SERRATE regulates the transcription of intronless genes
por: Speth, Corinna, et al.
Publicado: (2018)

Correction: Evidence that Mediator is essential for Pol II transcription, but is not a required component of the preinitiation complex in vivo
por: Petrenko, Natalia, et al.
Publicado: (2017)

Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle
por: Friman, Elias T, et al.
Publicado: (2019)

SNPC-1.3 is a sex-specific transcription factor that drives male piRNA expression in C. elegans
por: Choi, Charlotte P, et al.
Publicado: (2021)

Nup98-dependent transcriptional memory is established independently of transcription
por: Pascual-Garcia, Pau, et al.
Publicado: (2022)

Shadow enhancers can suppress input transcription factor noise through distinct regulatory logic
por: Waymack, Rachel, et al.
Publicado: (2020)

Computational prediction of CTCF/cohesin-based intra-TAD loops that insulate chromatin contacts and gene expression in mouse liver
por: Matthews, Bryan J, et al.
Publicado: (2018)

Amplification of a broad transcriptional program by a common factor triggers the meiotic cell cycle in mice
por: Kojima, Mina L, et al.
Publicado: (2019)

Cis-regulatory evolution integrated the Bric-à-brac transcription factors into a novel fruit fly gene regulatory network
por: Roeske, Maxwell J, et al.
Publicado: (2018)

Chromatin-associated RNA sequencing (ChAR-seq) maps genome-wide RNA-to-DNA contacts
por: Bell, Jason C, et al.
Publicado: (2018)

The nucleosome DNA entry-exit site is important for transcription termination and prevention of pervasive transcription
por: Hildreth, A Elizabeth, et al.
Publicado: (2020)

Transcriptional adaptation in Caenorhabditis elegans
por: Serobyan, Vahan, et al.
Publicado: (2020)

Genetic dissection of the RNA polymerase II transcription cycle
por: Chou, Shao-Pei, et al.
Publicado: (2022)

Universally high transcript error rates in bacteria
por: Li, Weiyi, et al.
Publicado: (2020)

Nucleotide-level linkage of transcriptional elongation and polyadenylation
por: Geisberg, Joseph V, et al.
Publicado: (2022)

Convergence of topological domain boundaries, insulators, and polytene interbands revealed by high-resolution mapping of chromatin contacts in the early Drosophila melanogaster embryo
por: Stadler, Michael R, et al.
Publicado: (2017)

SUMOylation of Bonus, the Drosophila homolog of Transcription Intermediary Factor 1, safeguards germline identity by recruiting repressive chromatin complexes to silence tissue-specific genes
por: Godneeva, Baira, et al.
Publicado: (2023)

Multi-enhancer transcriptional hubs confer phenotypic robustness
por: Tsai, Albert, et al.
Publicado: (2019)

Pervasive transcription fine-tunes replication origin activity
por: Candelli, Tito, et al.
Publicado: (2018)

The transcriptional elongation rate regulates alternative polyadenylation in yeast
por: Geisberg, Joseph V, et al.
Publicado: (2020)

Conserved noncoding transcription and core promoter regulatory code in early Drosophila development
por: Batut, Philippe J, et al.
Publicado: (2017)

A genetic program mediates cold-warming response and promotes stress-induced phenoptosis in C. elegans
por: Jiang, Wei, et al.
Publicado: (2018)

Mechanisms governing target search and binding dynamics of hypoxia-inducible factors
por: Chen, Yu, et al.
Publicado: (2022)

A bipartite iron-dependent transcriptional regulation of the tryptophan salvage pathway in Chlamydia trachomatis
por: Pokorzynski, Nick D, et al.
Publicado: (2019)

CRISPRi is not strand-specific at all loci and redefines the transcriptional landscape
por: Howe, Françoise S, et al.
Publicado: (2017)

The deubiquitylase Ubp15 couples transcription to mRNA export
por: Eyboulet, Fanny, et al.
Publicado: (2020)

A non-canonical role for the EDC4 decapping factor in regulating MARF1-mediated mRNA decay
por: Brothers, William R, et al.
Publicado: (2020)

Allele-specific gene expression can underlie altered transcript abundance in zebrafish mutants
por: White, Richard J, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_05mkgqtiv7r7lvbesrrebpp06i