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Extension of the minimal functional unit of the RNA polymerase II CTD from yeast to mammalian cells

The carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II) consists of 26 and 52 heptad-repeats in yeast and mammals, respectively. Studies in yeast showed that the strong periodicity of the YSPTSPS heptads is dispensable for cell growth and that di-heptads interspersed b...

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Detalles Bibliográficos
Autores principales: Shah, Nilay, Decker, Tim-Michael, Eick, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548728/
https://www.ncbi.nlm.nih.gov/pubmed/31088280
http://dx.doi.org/10.1098/rsbl.2019.0068